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A Pediatric Case Report of Fixed Drug Eruption Related to Carmoisine Colorant Present in Paracetamol Syrup

A Pediatric Case Report of Fixed Drug Eruption Related to Carmoisine Colorant Present in Paracetamol Syrup

George Mathew Panachiyil, Tirin Babu, Juny Sebastian, Narayanappa Doddaiah

Indian J Pharmacol. Jul-Aug 2019;51(4):279-281.

PMID: 31571716

Abstract:

Various adverse drug reactions, including hypersensitivity skin reaction after the exposure to carmoisine colorant, have already been reported in the literature. This case report gives the details of a 5-year-old male child with a recurrent fixed drug eruption (FDE) over the neck and trunk after the use of paracetamol syrup containing carmoisine as a colorant. Patch test to the carmoisine colorant in the paracetamol syrup was positive. This case report adds an increased awareness of the probability of allergic skin reaction to carmoisine in a previously sensitized person. The report also emphasizes the necessity to consider artificial dyes in pharmaceutical products as a potential cause for FDE.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP3567699	Carmoisine		3567-69-9	Price

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