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A Review of Nicotinamide: Treatment of Skin Diseases and Potential Side Effects

A Review of Nicotinamide: Treatment of Skin Diseases and Potential Side Effects

Heidi M Rolfe

J Cosmet Dermatol. 2014 Dec;13(4):324-8.

PMID: 25399625

Abstract:

Nicotinamide, also known as niacinamide, is the amide form of vitamin B3. It is a precursor of essential coenzymes for numerous reactions in the body including adenosine triphosphate (ATP) production. Nicotinic acid, also known as niacin, is converted into nicotinamide in the body. The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed. The possible side effects and consequences of excessive nicotinamide exposure are reviewed, including suggestions nicotinamide might have a role in the development of diabetes, Parkinson's disease, and liver damage.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP98920-B	Niacinamide		98-92-0	Price

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