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A Review of Syntheses of 1,5-disubstituted Tetrazole Derivatives

A Review of Syntheses of 1,5-disubstituted Tetrazole Derivatives

Afshin Sarvary, Ali Maleki

Mol Divers. 2015 Feb;19(1):189-212.

PMID: 25273563

Abstract:

This report provides a brief overview of the various representative literature procedures for the synthesis of 1,5-disubstituted tetrazoles (1,5-DSTs) and fused 1,5-disubstituted tetrazoles with more than 120 references. Most of the published methods for the synthesis of 1,5-DSTs include the use of nitriles, amides, thioamides, imidoyl chlorides, heterocumulenes, isocyanates, isothiocyanates, carbodiimides, ketenimines, ketones, amines, and alkenes as the starting materials. The transformation of 1- and 5-substituted tetrazoles into 1,5-DSTs is also covered in this report.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP919973834	OF-1		919973-83-4	Price

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