Home
Resources
Publications
A Rice Gene That Confers Broad-Spectrum Resistance to β-triketone Herbicides

A Rice Gene That Confers Broad-Spectrum Resistance to β-triketone Herbicides

Hideo Maeda, Kazumasa Murata, Nozomi Sakuma, Satomi Takei, Akihiko Yamazaki, Md Rezaul Karim, Motoshige Kawata, Sakiko Hirose, Makiko Kawagishi-Kobayashi, Yojiro Taniguchi, Satoru Suzuki, Keisuke Sekino, etc.

Science. 2019 Jul 26;365(6451):393-396.

PMID: 31346065

Abstract:

The genetic variation of rice cultivars provides a resource for further varietal improvement through breeding. Some rice varieties are sensitive to benzobicyclon (BBC), a β-triketone herbicide that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD). Here we identify a rice gene, HIS1 (HPPD INHIBITOR SENSITIVE 1), that confers resistance to BBC and other β-triketone herbicides. We show that HIS1 encodes an Fe(II)/2-oxoglutarate-dependent oxygenase that detoxifies β-triketone herbicides by catalyzing their hydroxylation. Genealogy analysis revealed that BBC-sensitive rice variants inherited a dysfunctional his1 allele from an indica rice variety. Forced expression of HIS1 in Arabidopsis conferred resistance not only to BBC but also to four additional β-triketone herbicides. HIS1 may prove useful for breeding herbicide-resistant crops.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AS2121337	Herbicides			Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: