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A Sequential Double Blind Cross-Over Trial of Tocainide Hydrochloride in Tinnitus

A W Blayney, M S Phillips, A M Guy, B H Colman

Clin Otolaryngol Allied Sci. 1985 Apr;10(2):97-101.

PMID: 3928215

Abstract:

A sequential double blind cross-over trial of tocainide hydrochloride, an oral analogue of lignocaine, is reported. The dosage of tocainide hydrochloride ranged from 200-600 mg daily. Of the 32 patients who completed the trial, 1 had complete relief and 2 had partial relief of their tinnitus whilst taking tocainide. An increased incidence of side-effects in patients taking tocainide was noted, in particular, headache, dizziness, nausea and skin rashes.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP71395147-A Tocainide hydrochloride Tocainide hydrochloride 71395-14-7 Price
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