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A Trifluoromethylcarbene Source

Yaya Duan, Jin-Hong Lin, Ji-Chang Xiao, Yu-Cheng Gu

Org Lett. 2016 May 20;18(10):2471-4.

PMID: 27169696

Abstract:

The trifluoromethylcarbene (:CHCF3) was found to be conveniently generated from (2,2,2-trifluoroethyl)diphenyl-sulfonium triflate (Ph2S(+)CH2CF3 (-)OTf), which was successfully applied in Fe-catalyzed cyclopropanation of olefins, giving the corresponding trifluoromethylated cyclopropanes in high yields.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP180801552 Boc-methoxyphenyldiphenylsulfonium triflate Boc-methoxyphenyldiphenylsulfonium triflate 180801-55-2 Price
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