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Abnormal N-Nonacosane Storage in Humans: Detection by Gas chromatography/mass Spectrometry of Tissue Extracts

F Rocchiccioli, A Lageron, C Duboucher

Biomed Environ Mass Spectrom. 1987 Sep;14(9):481-5.

PMID: 2960393

Abstract:

We report a case of n-nonacosane storage disease, which went undiagnosed until the death of a 55-year-old farmer. Clinical, histological, and biochemical features are discussed. n-Nonacosane storage was identified by gas chromatographic-mass spectrometric analysis of different tissue extracts, n-nonacosane concentration reaching 1.2 mg g-1 of lung tissue and 0.32 mg g-1 of liver tissue. It was possible to rule out a work-induced intoxication, and n-nonacosane storage appeared to be accounted for by a lifelong, heavy consumption of unpeeled apples and Brussels sprouts.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP630035 Nonacosane Nonacosane 630-03-5 Price
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