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[Activity of Topical Flunoxaprofen in Nonspecific Vaginitis. Comparison With Meclocycline Sulfosalicylate]

V Facchini, G Rispoli, F Dubini, P Bignami, C Sacchi

Minerva Ginecol. 1989 Dec;41(12):609-14.

PMID: 2626206

Abstract:

A trial was performed in 30 patients affected by non-specific vaginitis. The results show that the topical application (by vaginal washings) of flunoxaprofen produces a high therapeutic activity like that of meclocycline. Contrary to meclocycline, flunoxaprofen does not possess bactericidal and bacteriostatic properties. Therefore, the normalization of vaginal flora, with a remarkable increase of Döderlein bacillus, is exclusively due to local antiphlogistic activity of flunoxaprofen. Contrary to meclocycline, flunoxaprofen induces a precocious increase of Döderlein bacillus, necessary for a definitive normalization and to limit the possibility of relapses.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP73816429 Meclocycline sulfosalicylate Meclocycline sulfosalicylate 73816-42-9 Price
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