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Alclometasone Dipropionate Cream 0.05% Versus Clobetasone Butyrate Cream 0.05%. A Controlled Clinical Comparison in the Treatment of Atopic Dermatitis in Children

Alclometasone Dipropionate Cream 0.05% Versus Clobetasone Butyrate Cream 0.05%. A Controlled Clinical Comparison in the Treatment of Atopic Dermatitis in Children

A Lassus

Int J Dermatol. 1984 Oct;23(8):565-6.

PMID: 6389385

Abstract:

A randomized, double-blind, parallel-group study was conducted comparing the efficacy and safety of alclometasone dipropionate cream 0.05% and clobetasone butyrate cream 0.05% in the treatment of atopic dermatitis in 43 children. The medications were applied to study areas as a thin layer of cream twice daily for 2 weeks. Efficacy was assessed by evaluation of three disease signs (erythema, induration, and pruritus) and by mean of a physician's global evaluation following treatment. Safety was evaluated through patient-reported and clinically observed adverse experiences. Both treatments were effective. At the end of the trial, average reduction in disease signs was 85% for alclometasone dipropionate-treated patients and 86% in the clobetasone butyrate-treated group. In the global evaluation, the physician rated symptoms as cleared in 9 of 22 alclometasone dipropionate-treated patients and in 10 of 21 clobetasone butyrate-treated patients.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP66734132	Alclometasone dipropionate		66734-13-2	Price

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