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Alkylacylglycerol Molecular Species in the Glycosylinositol Phospholipid Membrane Anchor of Bovine Erythrocyte Acetylcholinesterase

W L Roberts, J J Myher, A Kuksis, T L Rosenberry

Biochem Biophys Res Commun. 1988 Jan 15;150(1):271-7.

PMID: 3337715

Abstract:

Bovine erythrocyte acetylcholinesterase, a glycosylinositol phospholipid anchored membrane enzyme, was digested with phosphatidylinositol-specific phospholipase C and the released glycerol-containing moieties were identified and quantitated. About 96% of the total was alkylacylglycerol, of which sn-1-stearyl-2-stearoylglycerol, sn-1-stearyl-2-oleoylglycerol and sn-1-oleyl-2-stearoylglycerol accounted for 69%, 13% and 10%, respectively. These alkylacylglycerols are in marked contrast to the exclusively diacylglycerol species present in phosphatidylinositol from bovine erythrocyte membranes. This difference suggests that assembly of the membrane anchor of Ebo AChE involves a selected cellular pool of diradylglycerols.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP621614 2-Stearoylglycerol 2-Stearoylglycerol 621-61-4 Price
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