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Allylation and Crotylation of Ketones and Aldehydes Using Potassium Organotrifluoroborate Salts Under Lewis Acid and Montmorillonite K10 Catalyzed Conditions

Farhad Nowrouzi, Avinash N Thadani, Robert A Batey

Org Lett. 2009 Jun 18;11(12):2631-4.

PMID: 19473013

Abstract:

Two convenient highly diastereoselective protocols for the allylation and crotylation of ketones using practical, air- and water-stable potassium allyl and crotyltrifluoroborate salts have been developed. BF(3).OEt(2) and montmorillonite clay are used as catalysts to promote additions. The montmorillonite-catalyzed method in particular is very robust, providing a straightforward and scalable method for the allylation and crotylation of a range of ketones and aldehydes.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP329976796 Potassium octyltrifluoroborate Potassium octyltrifluoroborate 329976-79-6 Price
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