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Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-crown-6 in Aqueous Media

Fernanda C G Barbosa, Juliano C R Freitas, Caio F Melo, Paulo H Menezes, Roberta A Oliveira

Molecules. 2012 Nov 28;17(12):14099-110.

PMID: 23192187

Abstract:

An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP233664534 Potassium allyltrifluoroborate Potassium allyltrifluoroborate 233664-53-4 Price
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