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Alternative Antimicrobials: The Properties of Fatty Acids and Monoglycerides

Colin P Churchward, Raid G Alany, Lori A S Snyder

Crit Rev Microbiol. 2018 Sep;44(5):561-570.

PMID: 29733249

Abstract:

With the rising antibiotic resistance of many bacterial species, alternative treatments are necessary to combat infectious diseases. The World Health Organization and the US Centres for Disease Control and Prevention have warned that some infections, such as those from Neisseria gonorrhoeae, may be untreatable within a few years. One avenue of exploration is the use of antimicrobial fatty acids and their derivatives for therapeutic prevention or treatment of bacterial infections. Several studies have explored the activity of fatty acids and their derivatives, including monoglycerides against a variety of bacterial species. These are reviewed here, assessing the antimicrobial properties that have been demonstrated and the feasibility of therapeutic applications.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP68990534 Monoglycerides Monoglycerides 68990-53-4 Price
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