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Aminobenzoic Acid Incorporated Octapeptides for Cation Transport

Bahiru P Benke, Nandita Madhavan

Bioorg Med Chem. 2015 Apr 1;23(7):1413-20.

PMID: 25766627

Abstract:

Robust oligopeptides that mimic natural ion channels are attractive for use as molecular switches or model systems to study ion transport. Herein, we report octapeptides derived from aminobenzoic acid and l/d amino acids. Two of the alanine containing peptides were found to be most active and the peptide containing p-aminobenzoic acid was found to be most active (2.4 times its m-analog). Experimental studies indicate the peptides do not transport halides and transport alkali metal ions.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP150130-B Aminobenzoic acid Aminobenzoic acid 150-13-0 Price
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