Home
Resources
Publications
Amphetamine and Other Pharmacological Agents in Human and Animal Studies of Recovery From Stroke

Amphetamine and Other Pharmacological Agents in Human and Animal Studies of Recovery From Stroke

D Walker-Batson, J Mehta, P Smith, M Johnson

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4;64:225-30.

PMID: 25896190

Abstract:

Neuromodulation with pharmacological agents, including drugs of abuse such as amphetamine, when paired with behavioral experience, has been shown to positively modify outcomes in animal models of stroke. A number of clinical studies have tested the efficacy of a variety of drugs to enhance recovery of language deficit post-stroke. The purpose of this paper is to: (1) present pertinent animal studies supporting the use of dextro-amphetamine sulfate (AMPH) to enhance recovery after experimental lesions with emphasis on the importance of learning dependent activity for lasting recovery; (2) briefly review neuropharmacological explorations in the treatment of aphasia; (3) present a pilot study in aphasia exploring a drug combination of AMPH and donepezil hydrochloride paired with behavioral treatment to facilitate recovery; and (4) conclude with comments regarding the role of adjunctive pharmacotherapy in the rehabilitation of aphasia, particularly AMPH.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP39628110	Camfetamine hydrochloride		39628-11-0	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: