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An Advanced Tool To Interrogate BRD9

Rezaul M Karim, Ernst Schönbrunn

J Med Chem. 2016 May 26;59(10):4459-61.

PMID: 27120693

Abstract:

Selective inhibitors of bromodomain-containing protein 9 (BRD9) may have therapeutic potential in the treatment of human malignancies and inflammatory diseases. A selective small molecule inhibitor that is well tolerated and has proper pharmacokinetic properties is required to explore the function of BRD9 in diseases. BI-9564 (2) is a cell permeable and noncytotoxic BRD9 inhibitor provided to the scientific community to explore BRD9 biology and determine its potential as a drug target.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP1883429228 BI-9564 BI-9564 1883429-22-8 Price
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