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An Immuno-Potentiating Vehicle Made of Mesoporous Silica-Zinc Oxide Micro-Rosettes With Enhanced Doxorubicin Loading for Combined Chemoimmunotherapy

Guowen Qian, Xiupeng Wang, Xia Li, Atsuo Ito, Yu Sogo, Jiandong Ye

Chem Commun (Camb). 2019 Jan 17;55(7):961-964.

PMID: 30605205

Abstract:

Herein, mesoporous silica-zinc oxide (MS-Zn) micro-rosettes with controllable petal thickness were synthesized by a facile one-pot hydrothermal method. MS-Zn loaded with doxorubicin and polyinosinic-polycytidylic acid sodium salt not only significantly inhibits tumor growth but also effectively rejects tumor metastasis in vivo.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP42424500 Polyinosinic-polycytidylic acid sodium salt Polyinosinic-polycytidylic acid sodium salt 42424-50-0 Price
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