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An Isoindole Alkaloid From Portulaca Oleracea L

Mingyue Jiang, Wenjie Zhang, Xu Yang, Fen Xiu, Haoran Xu, Xixiang Ying, Didier Stien

Nat Prod Res. 2018 Oct;32(20):2431-2436.

PMID: 29272980

Abstract:

A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L. Compounds 2 and 7 were isolated for the first time from this plant. Compound 1 was identified using spectroscopic methods including HR-ESI-TOF-MS, 1D-NMR, 2D-NMR. It was tested in a nitric oxide (NO) inhibition assay and was shown to inhibit NO production in RAW 264.7 cells induced by LPS.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP36417864 N-trans-p-Coumaroyltyramine N-trans-p-Coumaroyltyramine 36417-86-4 Price
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