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Analytics of Quinine and Its Derivatives

Analytics of Quinine and Its Derivatives

Mariusz Kluska, Anna Marciniuk-Kluska, Dorota Prukała, Wiesław Prukała

Crit Rev Anal Chem. 2016;46(2):139-45.

PMID: 25831406

Abstract:

The objective of this study was to perform a synthesis and analysis of the most important information on quinine and its derivatives, which are still very important in the treatment of malaria. The analysis of stereoisomers of quinine and its derivatives was conducted using two techniques, high-performance liquid chromatography and capillary electrophoresis. Particularly noteworthy is the technique used for the determination of isotachophoresis, referred to as one of the so-called green chemistry techniques. Particular attention was paid to properties and the use of quinine and its derivatives in the treatment of malaria. The analytical part will supplement knowledge about quinidine, quinine, and cinchonidine, and will contribute to the growth of research on the so-much-needed drugs against malaria.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP130950-A	(-)-Quinine		130-95-0	Price

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