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Anatomic Peculiarities of Pig and Human Liver

Anatomic Peculiarities of Pig and Human Liver

Andriy Nykonenko, Petr Vávra, Pavel Zonča

Exp Clin Transplant. 2017 Feb;15(1):21-26.

PMID: 28122484

Abstract:

Many investigations on surgical methods and medical treatment are currently done on pigs. This is possible because the pig is sufficiently close genetically to humans. In recent years, progress in liver surgery has opened new possibilities in surgical treatment of liver diseases. Because the methods are relatively novel, various improvements are still needed, and it is thus helpful to conduct experimental surgeries on pig livers. We reviewed the literature to compare the anatomic and functional features of pig and human livers, information that will be of great importance for improving surgical techniques. During the literature review, we used various sources, such as PubMed, Scopus, and veterinary journals. Our results were summarized in diagrams to facilitate understanding of the vascular structure and biliary systems. We conclude that, although the shapes of the human and pig livers are quite different, the pig liver is divided into the same number of segments as the human liver, which also shows a common structure of the vascular system. Thus, with the anatomic and structural features of the pig liver taken into account, this animal model can be used in experimental hepatic surgery.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP61417467	Deamino-Tyr-β-Ala-secretin, pig		61417-46-7	Price

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