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Anti-inflammatory Furanogermacrane Sesquiterpenes From Neolitsea Parvigemma

Keh-Shaw Chen, Pei-Wen Hsieh, Tsong-Long Hwang, Fang-Rong Chang, Yang-Chang Wu

Nat Prod Res. 2005 Apr;19(3):283-6.

PMID: 15702642

Abstract:

Six furanogermacrane sesquiterpenes, pseudoneolinderane (1), linderalactone (2), zeylanidine (3), zeylanicine (4), deacetylzeylanidine (5), and neolitrane (6), isolated from the stems of Neolitsea parvigemma, were tested for anti-inflammatory activities. Among them, 1 and 2 showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB. The IC50 of 1 and 2 were found to be 3.21 and 8.48 microg/mL, respectively.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP728610 Linderalactone Linderalactone 728-61-0 Price
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