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Antibacterial Efficacy of Several Intracanal Medicaments for Endodontic Therapy

Antibacterial Efficacy of Several Intracanal Medicaments for Endodontic Therapy

Marta E Valverde, Pilar Baca, Laura Ceballos, M Victoria Fuentes, Matilde Ruiz-Linares, Carmen María Ferrer-Luque

Dent Mater J. 2017 May 31;36(3):319-324.

PMID: 28228624

Abstract:

The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded before and after medication. Samples were divided in two (2/7 days), and subdivided (n=8/group): triple antibiotic paste (TAP); double antibiotic paste (DAP); dental base paste (DBP), consisting of calcium hydroxide, propylene glycol and calcium carbonate; DBP+0.2% chlorhexidine (CHX); DBP+0.2% cetrimide (CTR); DBP+0.2% CHX+0.2% CTR; 2.5% sodium hypochlorite (NaOCl); and distilled water. At both periods TAP, DAP, DBP+0.2% CHX, DBP+0.2% CTR and DBP+0.2% CHX+0.2% CTR exhibited no growth (NG) of E. faecalis. Distilled water and 2.5% NaOCl obtained the lowest CFU reduction. No growth with DBP was reached only at 7 days. CHX and/or CTR pastes were as effective as DAP and TAP. A 2-day period provided an effective disinfection.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP175606050	DBP		175606-05-0	Price

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