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Antibacterial Evaluation of Cnicin and Some Natural and Semisynthetic Analogues

Maurizio Bruno, Sergio Rosselli, Antonella Maggio, Rosa Angela Raccuglia, Francesco Napolitano, Felice Senatore

Planta Med. 2003 Mar;69(3):277-81.

PMID: 12677537

Abstract:

Some ester derivatives of salonitenolide have been prepared from cnicin, a germacranolide sesquiterpenoid. The compounds were tested for their antibacterial activity. The 8,15-diesters showed a good activity, comparable with that of cnicin. The 15-monoester compounds were not very active showing that esterification at the C-8 position is an important structural feature for antibacterial properties.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP24394090 Cnicin Cnicin 24394-09-0 Price
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