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Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol

Danja J Den Hartogh, Evangelia Tsiani

Biomolecules. 2019 Mar 12;9(3):99.

PMID: 30871083

Abstract:

Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by insulin resistance and hyperglycemia and is associated with personal health and global economic burdens. Current strategies/approaches of insulin resistance and T2DM prevention and treatment are lacking in efficacy resulting in the need for new preventative and targeted therapies. In recent years, epidemiological studies have suggested that diets rich in vegetables and fruits are associated with health benefits including protection against insulin resistance and T2DM. Naringenin, a citrus flavanone, has been reported to have antioxidant, anti-inflammatory, hepatoprotective, nephroprotective, immunomodulatory and antidiabetic properties. The current review summarizes the existing in vitro and in vivo animal studies examining the anti-diabetic effects of naringenin.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP67604482-A (±)-Naringenin (±)-Naringenin 67604-48-2 Price
AP67604482-B Naringenin Naringenin 67604-48-2 Price
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