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Antimalarial Activity of Concanamycin A Alone and in Combination With Pyronaridine

Saranya Auparakkitanon, Prapon Wilairat

Southeast Asian J Trop Med Public Health. 2006 Jul;37(4):619-21.

PMID: 17121284

Abstract:

Concanamycin A, a macrolide antibiotic inhibitor of vacuolar H+-ATPase derived from Streptomyces sp, inhibited Plasmodium falciparum K1 growth in culture with an IC500 value of 0.2 nM. It exhibited an additive effect when tested together with the antimalarial pyronaridine.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP80890477 Concanamycin A Concanamycin A 80890-47-7 Price
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