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Antimicrobial Activity of Five Essential Oils From Lamiaceae Against Multidrug-Resistant

Antimicrobial Activity of Five Essential Oils From Lamiaceae Against Multidrug-Resistant

Barbara Kot, Kamila Wierzchowska, Małgorzata Piechota, Paweł Czerniewicz, Grzegorz Chrzanowski

Nat Prod Res. 2019 Dec;33(24):3587-3591.

PMID: 29888957

Abstract:

Analysis of Lamiaceae essential oils (EOs) by GC-FID-MS revealed the presence as the major constituents of linalool (16.8%), linalyl acetate (15.7%) in Lavandula angustifolia, menthol (29.0%), menthone (22.7%), menthyl acetate (19.2%) in Mentha x piperita, terpinen-4-ol (27.1%), (E)-sabinene hydrate (12.1%), γ-terpinene (10.0%) in Origanum majorana, α-thujone (19.5%), camphor (19.0%), viridiflorol (13.5%) in Salvia officinalis, thymol (61.9%), p-cymene (10.0%), γ-terpinene (10.0%) in Thymus vulgaris. Based on the MIC and MBC values (0.09-0.78 mg/mL) and ratio MBC/MIC showed that EO from T. vulgaris (TO) had the strong inhibitory and bactericidal effect against multidrug-resistant Staphylococcus aureus. The bacterial cells were total killed by TO at 2MIC concentration after 6 h. The higher concentrations of other EOs were needed to achieve bactericidal effects. The strong bactericidal effect of TO against these bacteria indicates the possibility of topical use of TO but it requires research under clinical conditions.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP552023	Viridiflorol		552-02-3	Price
AP89485	Menthyl acetate		89-48-5	Price

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