Home
Resources
Publications
Antioxidant and anti-adipogenic activities of chestnut ( Castanea crenata) byproducts

Antioxidant and anti-adipogenic activities of chestnut ( Castanea crenata) byproducts

Un-Young Youn, Myung-Soo Shon, Gyo-Nam Kim, Riho Katagiri, Kaori Harata, Yasuyuki Ishida, Seung-Cheol Lee

Food Sci Biotechnol. 2016 Aug 31;25(4):1169-1174.

PMID: 30263390

Abstract:

The antioxidant and anti-adipogenic activities of chestnut byproducts were evaluated. At 100 μg/mL, the methanol extract (ME) scavenged 34.2% of DPPH and 78.8% of ABTS radicals. The DPPH and ABTS radical scavenging activity of the water extract (WE) was found to be low (13.7 and 33.1%, respectively) compared with controls. WE and ME dose-dependently inhibited lipid accumulation of 3T3-L1 adipocytes. WE and ME at 100 μg/mL suppressed 3T3-L1 adipogenesis by 71.0 and 96.5%, respectively, when compared with mature adipocytes. The results indicated that WE and ME inhibited adipocyte differentiation by down-regulating the mRNA expression levels of CCAAT/enhancer binding protein (C/EBP)-β, C/EBPα, and peroxisome proliferator-activated receptor (PPAR)-γ in 3T3-L1 cells. Our study also revealed that WE and ME inhibited pre- and early stage adipogenesis in 3T3-L1 cells. The results suggest that chestnut byproducts are a promising source of antioxidant and antiobesity molecules.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42415835	ABTS Enhancer			Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: