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Antioxidant Response Element Activator, BTZO-1, Improves the Developmental Competence of Bovine Oocytes

Mansour Aboelenain, Wael B El Domany, Haitham Eldoumani, Wael A Khalil

Reprod Domest Anim. 2020 May 30.

PMID: 32473610

Abstract:

Increased reactive oxygen species (ROS) generation may disrupt the oocytes function and their competence. In this study, we introduced BTZO-1, a new supplement that can regulate the oxidative stress. Addition of BTZO-1 during IVM of bovine oocytes improved their developmental competence in the term of improvement of blastocyst rates. In addition, the quality of the produced embryos was improved by decreasing the apoptosis level by showing a decreased number of TUNNEL positive cells.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP99420152 BTZO-1 BTZO-1 99420-15-2 Price
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