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AOM/DSS Model of Colitis-Associated Cancer

Bobak Parang, Caitlyn W Barrett, Christopher S Williams

Methods Mol Biol. 2016;1422:297-307.

PMID: 27246042

Abstract:

Our understanding of colitis-associated carcinoma (CAC) has benefited substantially from mouse models that faithfully recapitulate human CAC. Chemical models, in particular, have enabled fast and efficient analysis of genetic and environmental modulators of CAC without the added requirement of time-intensive genetic crossings. Here we describe the Azoxymethane (AOM)/Dextran Sodium Sulfate (DSS) mouse model of inflammatory colorectal cancer.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP7757826-B Sodium sulfate Sodium sulfate 7757-82-6 Price
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