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Application of an (18-Crown-6)-2,3,11,12-Tetracarboxylic Acid-Based Chiral Stationary Phase in Capillary Electrochromatography

Wonjae Lee, Kyung Tae Kim, Jong Seong Kang

Methods Mol Biol. 2019;1985:445-452.

PMID: 31069751

Abstract:

Capillary electrochromatography is employed for the enantioseparation of α-amino acids and their derivatives. The synthesis and application of a covalently bonded chiral stationary phase containing (-)-(18-crown-6)-2,3,11,12-tetracarboxylic acid as chiral selector is described. Enantioseparations are performed using methanol/Tris-citric acid (20 mM, pH 3.0-4.5) (20:80, v/v) as mobile phase.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP17455139 18-Crown-6 18-Crown-6 17455-13-9 Price
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