Home
Resources
Publications
Application of Sweeping to Micellar Electrokinetic Chromatography-Atmospheric Pressure Chemical Ionization-Mass Spectrometric Analysis of Environmental Pollutants

Application of Sweeping to Micellar Electrokinetic Chromatography-Atmospheric Pressure Chemical Ionization-Mass Spectrometric Analysis of Environmental Pollutants

K Isoo, K Otsuka, S Terabe

Electrophoresis. 2001 Oct;22(16):3426-32.

PMID: 11669521

Abstract:

An application study of sweeping, an on-line sample concentration technique, to micellar electrokinetic chromatography (MEKC) directly combined with mass spectrometry (MS) using an atmospheric pressure chemical ionization (APCI) interface, namely MEKC-APCI-MS, was investigated to enhance the concentration sensitivity for the analysis of environmental pollutants. Under a neutral condition, around 100-fold increase in the concentration sensitivity was achieved for several aromatic amines and alkyl phthalates as test samples by sweeping-MEKC-APCI-MS compared to conventional MEKC-APCI-MS, whereas under an acidic condition, 100 to 600-fold sensitivity enhancement was gained for similar solutes. Linearity of the corrected peak area obtained in the mass chromatogram against the sample concentration was examined for 3,4-dichloroaniline and diisopropyl phthalate (DIPP). The estimated limits of detection for 3,4-dichloroaniline and DIPP were 0.6 and 0.4 ppm, respectively, in terms of the injected sample concentration.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP605458	Diisopropyl phthalate		605-45-8	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: