0

Application of Sweeping to Micellar Electrokinetic Chromatography-Atmospheric Pressure Chemical Ionization-Mass Spectrometric Analysis of Environmental Pollutants

K Isoo, K Otsuka, S Terabe

Electrophoresis. 2001 Oct;22(16):3426-32.

PMID: 11669521

Abstract:

An application study of sweeping, an on-line sample concentration technique, to micellar electrokinetic chromatography (MEKC) directly combined with mass spectrometry (MS) using an atmospheric pressure chemical ionization (APCI) interface, namely MEKC-APCI-MS, was investigated to enhance the concentration sensitivity for the analysis of environmental pollutants. Under a neutral condition, around 100-fold increase in the concentration sensitivity was achieved for several aromatic amines and alkyl phthalates as test samples by sweeping-MEKC-APCI-MS compared to conventional MEKC-APCI-MS, whereas under an acidic condition, 100 to 600-fold sensitivity enhancement was gained for similar solutes. Linearity of the corrected peak area obtained in the mass chromatogram against the sample concentration was examined for 3,4-dichloroaniline and diisopropyl phthalate (DIPP). The estimated limits of detection for 3,4-dichloroaniline and DIPP were 0.6 and 0.4 ppm, respectively, in terms of the injected sample concentration.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP605458 Diisopropyl phthalate Diisopropyl phthalate 605-45-8 Price
qrcode

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies
x