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Applications of Poly(ethylene Oxide) in Controlled Release Tablet Systems: A Review

Lulu Ma, Li Deng, Jianming Chen

Drug Dev Ind Pharm. 2014 Jul;40(7):845-51.

PMID: 24001212

Abstract:

To improve therapeutic effects and compatibility of patients, controlled release tablet systems based on polymers are of great interest for pharmaceutical technologies. Poly(ethylene oxide) (PEO) is a non-ionic linear hydrophilic and uncrosslinked polymer available in a number of molecular weights. It is synthesized by ethylene oxide and has many desirable properties for drug delivery applications. This review article aims to summary the recent developments on physicochemical properties of PEO and focus on the recent efforts and developments on PEO as oral controlled release matrix tablets, bioadhesive hydrophilic matrices and osmotic pump tablets. Commercial products employed PEO were also discussed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP25322683-Q Poly(ethylene oxide) Poly(ethylene oxide) 25322-68-3 Price
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