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[Appropriate Use of Benzodiazepines Zolpidem and Zopiclone in Diseases Attended in Primary Care]

[Appropriate Use of Benzodiazepines Zolpidem and Zopiclone in Diseases Attended in Primary Care]

M Isabel Granados Menéndez, Miguel Angel Salinero Fort, Marta Palomo Ancillo, Laura Aliaga Gutiérrez, Carmen García Escalonilla, Rebeca Ortega Orcos

Aten Primaria. Jul-Aug 2006;38(3):159-64.

PMID: 16945275

Abstract:

Objectives:
To estimate the proportion of benzodiazepine prescriptions that comply with the guidelines for appropriate prescription. To identify the variables associated with appropriate prescription.
Design:
Observational, cross-sectional study.
Setting:
Monóvar Health Centre in Area IV, Madrid, Spain.
Subjects:
Random sample of 270 active benzodiazepine prescriptions in adult patients from the prescriptions record of the OMI-AP V. 5.0 computer system.
Measurements:
The chosen dimensions for appropriate prescription were: a) correct diagnostic indication; b) absence of benzodiazepines with long half-life in the elderly; c) existence of support or monitoring visits; d) overall appropriateness or coexistence of correct diagnostic indications and monitoring visits. Independent variables were recorded in relation to patient, person prescribing and prescription.
Results:
Diagnostic indication, 75.6%; absence of benzodiazepines with long half-life in the elderly, 79.8%; existence of support visits, 63.3%; overall appropriateness, 53%. Main diagnoses: pure anxiety, 29%; anxiety related to other illness, 18.6%; insomnia, 14.8%; cardiovascular illness, 14.8%; alcohol and drug abuse, 4.5%; osteo-muscular illness, 4.4%; schizophrenia, 4.4%. Most prescribed substances: lorazepam, 27.8%; bromazepam, 23.7%. Average life of prescriptions: 18.58 months. Origins: health centre, 68.5%; out-patient psychiatry, 10%; hospital, 10%. The variable that is most closely associated with overall appropriateness, fitted with the rest of the variables, is out-patient psychiatry prescription (OR, 6.67; 95% CI, 1.92-23.18).
Conclusions:
The mean duration of the prescriptions infringes all standards. The overall appropriateness or correct coexistence of adequate diagnostic indication with follow-up visits is associated with out-patient Psychiatry prescription.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP54643797	Lorazepam Related Compound D		54643-79-7	Price

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