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AraC Protein, Regulation of the L-Arabinose Operon in Escherichia Coli, and the Light Switch Mechanism of AraC Action

AraC Protein, Regulation of the L-Arabinose Operon in Escherichia Coli, and the Light Switch Mechanism of AraC Action

Robert Schleif

FEMS Microbiol Rev. 2010 Sep;34(5):779-96.

PMID: 20491933

Abstract:

This review covers the physiological aspects of regulation of the arabinose operon in Escherichia coli and the physical and regulatory properties of the operon's controlling gene, araC. It also describes the light switch mechanism as an explanation for many of the protein's properties. Although many thousands of homologs of AraC exist and regulate many diverse operons in response to many different inducers or physiological states, homologs that regulate arabinose-catabolizing genes in response to arabinose were identified. The sequence similarities among them are discussed in light of the known structure of the dimerization and DNA-binding domains of AraC.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP5328370	Arabinose		5328-37-0	Price

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