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Azatadine Maleate (Zadine): Evaluation in the Management of Allergic Rhinitis

Azatadine Maleate (Zadine): Evaluation in the Management of Allergic Rhinitis

J D Wilson, J L Hillas, S D Somerfield

N Z Med J. 1981 Aug 12;94(689):79-81.

PMID: 7024868

Abstract:

Azatadine maleate (Zadine), a new antihistamine, was evaluated for its efficacy in 20 patients with chronic allergic rhinitis. Eighty percent of patients had symptomatic relief with a twice daily dosage of 2 mg. Sedation was volunteered as a side effect by six of the patients and was admitted by two further patients after specific questioning. A choice reaction time test gave slowing of motor function in these sedated patients. Four of the previously sedated patients experienced good symptomatic control with minimal sedation when the azatadine dose was reduced to 1 mg twice daily; slowing of motor function was not observed at this, the normal recommended dose.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP3978867	Azatadine maleate		3978-86-7	Price

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