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Benzeneboronic Acid Selectively Inhibits Sporulation of Bacillis Subtilis

Benzeneboronic Acid Selectively Inhibits Sporulation of Bacillis Subtilis

K Davis-Mancini, I P Lopez, J H Hageman

J Bacteriol. 1978 Nov;136(2):625-30.

PMID: 30755

Abstract:

m-Aminobenzeneboronic acid at levels of 0.2 mM in nutrient broth medium selectively inhibited sporulation without appreciably altering vegetative growth. Significant inhibitory effects were seen even when it was added as late as 6 h after the end of logarithmic growth. The pH changes associated with growth and sporulation of Bacillus subtilis in nutrient broth were not significantly altered by the inhibitor. When it was present in cultures of actively growing cells, its inhibitory effect could not be reversed by simple dilution. The compound caused extensive clumping, of cells, which appeared not to be related to the ability of boronates to esterify to diols.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
LS793912	2-(e-cyanovinyl)benzeneboronic acid			Price
LS793929	(4-allylaminocarbonyl)benzeneboronic acid			Price

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