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Bioactive Constituents of Homalomena Aromatica Essential Oil and Its Antifungal Activity Against Dermatophytes and Yeasts

Bioactive Constituents of Homalomena Aromatica Essential Oil and Its Antifungal Activity Against Dermatophytes and Yeasts

R S Policegoudra, S Goswami, S M Aradhya, S Chatterjee, S Datta, R Sivaswamy, P Chattopadhyay, L Singh

J Mycol Med. 2012 Mar;22(1):83-7.

PMID: 23177818

Abstract:

Homalomena aromatica rhizomes are rich source of essential oils, which have been attributed for various medicinal uses. In the present investigation, essential oil from H. aromatica rhizomes was isolated and subjected to gas chromatography-mass spectrum (GC-MS) analysis. Fifty-five chemical constituents were reported from H. aromatica rhizomes of which T-muurolol (5.32%), viridiflorol (3.69%), α-selinene (2.19%), M-cymene (2.19%) and γ-Muurolene (1.81%) were identified and reported for the first time. Other major components were identified as linalool (62.5%), terpene-4-ol (7.08%), δ-cadinene (5.57%), α-cadinol (3.71%) and spatulenol (1.81%). H. aromatica rhizome essential oil showed high antimicrobial activity against Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum fulvum, Microsporum gypseum, Trichosporon beigelii and Candida albicans.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP535773	m-Cymene		535-77-3	Price

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