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Bioactive Indole Alkaloids From the Bark of Uncaria Guianensis

K K Lee, B N Zhou, D G Kingston, A J Vaisberg, G B Hammond

Planta Med. 1999 Dec;65(8):759-60.

PMID: 10630124

Abstract:

Bioassay-guided fractionation of the EtOH extract of the bark of Uncaria guianensis (Aubl.) Gmel (Rubiaceae) using a yeast-based assay for DNA-damaging agents has furnished the two weakly but selectively active indole alkaloids uncarine C (1) and uncarine E (2) as the major bioactive constituents in this assay.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP5171379-A Uncarine E Uncarine E 5171-37-9 Price
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