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Bioactivity Profile of the Diterpene Isosteviol and Its Derivatives

Bioactivity Profile of the Diterpene Isosteviol and Its Derivatives

Asad Ullah, Sidra Munir, Yahia Mabkhot, Syed Lal Badshah

Molecules. 2019 Feb 14;24(4):678.

PMID: 30769819

Abstract:

Steviosides, rebaudiosides and their analogues constitute a major class of naturally occurring biologically active diterpene compounds. The wide spectrum of pharmacological activity of this group of compounds has developed an interest among medicinal chemists to synthesize, purify, and analyze more selective and potent isosteviol derivatives. It has potential biological applications and improves the field of medicinal chemistry by designing novel drugs with the ability to cope against resistance developing diseases. The outstanding advancement in the design and synthesis of isosteviol and its derivative has proved its effectiveness and importance in the field of medicinal chemical research. The present review is an effort to integrate recently developed novel drugs syntheses from isosteviol and potentially active pharmacological importance of the isosteviol derivatives covering the recent advances.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP27975195	Isosteviol		27975-19-5	Price

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