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Bioavailability and Pharmacokinetics of Magnesium After Administration of Magnesium Salts to Humans

V V Ranade, J C Somberg

Am J Ther. Sep-Oct 2001;8(5):345-57.

PMID: 11550076

Abstract:

Therapeutically, magnesium salts represent an important class of compounds and exhibit various pharmacologic actions. Examples of magnesium salts are ionic magnesium and magnesium citrate in nephrolithiasis, magnesium salicylate in rheumatoid arthritis, magnesium hydroxide as an antacid as well as a cathartic, and magnesium mandelate as urinary antiseptic. Various anions attached to the cation magnesium, such as oxide, chloride, gluconate, and lactate, affect the delivery of the amounts of elemental magnesium to the target site and thereby produce different pharmacodynamic effects. This review examines the bioavailability and pharmacokinetics of various magnesium salts and correlates pharmacodynamic action with the structure-activity relationship.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP1309428-A Magnesium hydroxide Magnesium hydroxide 1309-42-8 Price
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