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Biocatalytic Plastics as Active and Stable Materials for Biotransformations

Biocatalytic Plastics as Active and Stable Materials for Biotransformations

P Wang, M V Sergeeva, L Lim, J S Dordick

Nat Biotechnol. 1997 Aug;15(8):789-93.

PMID: 9255796

Abstract:

Enzyme-containing polymeric materials have been developed that have high activity and stability in both aqueous and organic media. These biocatalytic plastics, containing alpha-chymotrypsin and subtilisin Carlsberg, can contain up to 50% (w/w) total protein in plastic materials such as poly(methyl methacrylate, styrene, vinyl acetate, and ethyl vinyl ether). The activation achieved in organic solvents by incorporating proteases in plastic matrices allows for the efficient synthesis of peptides, and sugar and nucleoside esters. The marriage of enzyme technology with polymer chemistry opens up an array of unique applications for plastic enzymes, including active and stable biocatalysts in paints, coatings, resins, foams, and beads, as well as membranes, fibers, and tubings.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP25104374	Poly(ethyl vinyl ether)		25104-37-4	Price

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