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Biodegradation of Phytane (2,6,10,14-tetramethylhexadecane) and Accumulation of Related Isoprenoid Wax Esters by Mycobacterium Ratisbonense Strain SD4 Under Nitrogen-Starved Conditions

Roxana A Silva, Vincent Grossi, Héctor M Alvarez

FEMS Microbiol Lett. 2007 Jul;272(2):220-8.

PMID: 17521403

Abstract:

The accumulation of storage lipids during the biodegradation of 2,6,10,14-tetramethylhexadecane (phytane) by Mycobacterium ratisbonense strain SD4 grown under nitrogen-starved conditions was investigated. Detailed chemical analysis of intracellular metabolites revealed the existence of (at least) three different pathways for the catabolism of phytane, and the accumulation of significant proportions (39% of the total lipids) of several isoprenoid wax esters formed by condensation of oxidation products of the hydrocarbon. In contrast, triacylglycerols but no wax esters were accumulated by strain SD4 grown on hexadecane, the unbranched homologue of phytane.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP638368 Phytane Phytane 638-36-8 Price
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