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Biological Activity of Secondary Metabolites From Peltostigma Guatemalense

Luis Enrique Cuca Suarez, Manuel Elkin Pattarroyo, Jose Manuel Lozano, Franco Delle Monache

Nat Prod Res. 2009;23(4):370-4.

PMID: 19296377

Abstract:

Leaves and wood of Peltostigma guatemalense, a novel species of the family Rutaceae, yielded a total of 14 secondary metabolites, i.e. methyl p-hydroxy benzoate, phenylacetic acid, beta-sitosterol, lupeol, syringaresinol, scopoletin, gardenin B (1), and seven alkaloids: gamma-fagarine (2), skimmianine (3), kokusaginine (4), 7-O-isopentenyl-gamma-fagarine (5), anhydro-evoxine (6), evoxine (7) and 4-methoxy-1-methyl-quinolin-2-one (8). The compounds have been identified by spectroscopic methods. Antibacterial and antimalarial in vitro activity of the isolated compounds were also determined. Methyl p-hydroxy benzoate and quinolone (8) were the most effective on Plasmodium falciparium strains.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP2798201 Gardenin B Gardenin B 2798-20-1 Price
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