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Biomacromolecules as Carriers in Drug Delivery and Tissue Engineering

Biomacromolecules as Carriers in Drug Delivery and Tissue Engineering

Yujie Zhang, Tao Sun, Chen Jiang

Acta Pharm Sin B. 2018 Jan;8(1):34-50.

PMID: 29872621

Abstract:

Natural biomacromolecules have attracted increased attention as carriers in biomedicine in recent years because of their inherent biochemical and biophysical properties including renewability, nontoxicity, biocompatibility, biodegradability, long blood circulation time and targeting ability. Recent advances in our understanding of the biological functions of natural-origin biomacromolecules and the progress in the study of biological drug carriers indicate that such carriers may have advantages over synthetic material-based carriers in terms of half-life, stability, safety and ease of manufacture. In this review, we give a brief introduction to the biochemical properties of the widely used biomacromolecule-based carriers such as albumin, lipoproteins and polysaccharides. Then examples from the clinic and in recent laboratory development are summarized. Finally the current challenges and future prospects of present biological carriers are discussed.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP123938863	Glycol chitosan		123938-86-3	Price

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