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Biosynthesis of the Antibiotic Tropodithietic Acid by the Marine Bacterium Phaeobacter Inhibens

Nelson L Brock, Alexander Nikolay, Jeroen S Dickschat

Chem Commun (Camb). 2014 May 28;50(41):5487-9.

PMID: 24723119

Abstract:

The biosynthesis of tropodithietic acid was investigated using a combinatorial approach of feeding experiments, gene knockouts and bioinformatic analyses. The mechanism of sulfur introduction is distinct from known mechanisms in holomycin, thiomarinol A and gliotoxin biosynthesis.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP750590182 Tropodithietic acid Tropodithietic acid 750590-18-2 Price
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