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Biotransformation of a Major Beer Prenylflavonoid - Isoxanthohumol

Biotransformation of a Major Beer Prenylflavonoid - Isoxanthohumol

Agnieszka Bartmańska, Tomasz Tronina, Jarosław Popłoński

Z Naturforsch C J Biosci. 2018 Dec 19;74(1-2):1-7.

PMID: 30864390

Abstract:

Microbial transformations of isoxanthohumol (1), a beer prenylated flavonoid, by 51 fungi were investigated. Many of the tested fungi cultures were capable of effective transformation of 1. Mucor hiemalis and Fusarium oxysporum converted isoxanthohumol (1) into isoxanthohumol 7-O-β-d-glucopyranoside (3) and (2R)-2″-(2″'-hydroxyisopropyl)-dihydrofurano[2″,3″:7,8]-4″,5-hydroxy-5-methoxyflavanone (4), respectively. No product was obtained in the transformation of 1 by Absidia glauca conducted in a phosphate buffer. In the same medium, Beauveria bassiana converted isoxanthohumol (1) to isoxanthohumol 7-O-β-d-4″'-O-methylglucopyranoside (2).

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP521482	Isoxanthohumol		521-48-2	Price

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