Home
Resources
Publications
Biotransformation of Ginsenoside Rb1 to Ginsenoside C-K by Endophytic Fungus Arthrinium Sp. GE 17-18 Isolated From Panax Ginseng

Biotransformation of Ginsenoside Rb1 to Ginsenoside C-K by Endophytic Fungus Arthrinium Sp. GE 17-18 Isolated From Panax Ginseng

Y Fu, Z-H Yin, L-P Wu, C-R Yin

Lett Appl Microbiol. 2016 Sep;63(3):196-201.

PMID: 27316666

Abstract:

This research aimed to isolate β-glycosidase-producing endophytic fungus in Panax ginseng to achieve biotransformation of ginsenoside Rb1 to ginsenoside C-K. Of these 15 β-glucosidase-producing endophytic fungus isolated from ginseng roots, a β-glucosidase-producing endophytic fungi GE 17-18 could hydrolyse major ginsenosides Rb1 to minor ginsenoside C-K with metabolic pathways: ginsenoside Rb1→ginsenoside Rd→ginsenoside F2→ginsenoside C-K. Phylogenetic analysis of ITS gene sequences indicated that the strain GE 17-18 belongs to the genus Arthrinium and is most closely related to Arthrinium sp. HQ832803.1.
Significance and impact of the study:
This is the first study to provide information of cultivable β-glycosidase-producing Endophytic fungus in Panax ginseng. The strain GE 17-18 has potential to be applied on the preparation for minor ginsenoside C-K in pharmaceutical industry.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP39262141	Ginsenoside C-K		39262-14-1	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: