Home
Resources
Publications
Bone Graft Substitutes: Current Concepts and Future Expectations

Bone Graft Substitutes: Current Concepts and Future Expectations

David C Lobb, Brent R DeGeorge Jr, A Bobby Chhabra

J Hand Surg Am. 2019 Jun;44(6):497-505.e2.

PMID: 30704784

Abstract:

Owing to its osteoinductive and osteoconductive properties and the presence of osteogenic cells, freshly harvested autologous bone graft is the gold standard for skeletal reconstruction where there is inadequate native bone. Whereas these characteristics are difficult to replicate, engineered, commercially available bone graft substitutes aim to achieve a comparable osseoregenerative profile. This work furnishes the reader with an understanding of the predominant classes of bone graft substitutes available for reconstruction of upper extremity bone defects following trauma or oncological surgery. We review bone graft substitutes with respect to their mechanisms of action, their advantages and disadvantages, and their indications and contraindications. We provide examples of bone graft substitutes in clinical use and outline comparative costs. We also describe the future directions for this specific aspect of reconstructive surgery with a focus on the role of bioactive glass.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AS212791	Acidity Standard			Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: