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Burkholderia Cepacia Lipase: A Versatile Catalyst in Synthesis Reactions

Burkholderia Cepacia Lipase: A Versatile Catalyst in Synthesis Reactions

Daniel A Sánchez, Gabriela M Tonetto, María L Ferreira

Biotechnol Bioeng. 2018 Jan;115(1):6-24.

PMID: 28941272

Abstract:

The lipase from Burkholderia cepacia, formerly known as Pseudomonas cepacia lipase, is a commercial enzyme in both soluble and immobilized forms widely recognized for its thermal resistance and tolerance to a large number of solvents and short-chain alcohols. The main applications of this lipase are in transesterification reactions and in the synthesis of drugs (because of the properties mentioned above). This review intends to show the features of this enzyme and some of the most relevant aspects of its use in different synthesis reactions. Also, different immobilization techniques together with the effect of various compounds on lipase activity are presented. This lipase shows important advantages over other lipases, especially in reaction media including solvents or reactions involving short-chain alcohols.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP9001621-F	Lipase from Pseudomonas cepacia		9001-62-1	Price
IAR42416025	Amano Lipase PS, from Burkholderia cepacia			Price

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