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Cantharidin Biosynthesis in a Blister Beetle: Inhibition by 6-fluoromevalonate Causes Chemical Disarmament

J E Carrel, J P Doom, J P McCormick

Experientia. 1986 Jul 15;42(7):853-4.

PMID: 3732495

Abstract:

Biosynthesis of cantharidin in a blister beetle, Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is attributed specifically to the fluorine substituent. Biochemical inhibition has not been demonstrated previously for an arthropod's defensive substance.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP2822777 6-Fluoromevalonate 6-Fluoromevalonate 2822-77-7 Price
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